Posting on X, Ukraine's Defence Ministry showed footage from the camera mounted on the drone as it homed in on its target.
The drone hit the vehicle front-on, immediately causing a huge explosion.
The footage did not specify where in Ukraine the incident took place but said the attack was carried out by the Ukrainian Territorial Defence's 109th Bridgade.
Accompanied with the video was the caption: "Say hello to Ukrainian FPV drone. Say goodbye to Ukrainian land."
The European Union has passed £50billion's worth of military aid while the US' aid package remains held up by Republican lawmakers in Washington DC.
In recent weeks, Russian President Vladimir Putin has warned of nuclear war after French President Emmanuel Macron said that Western troops could be sent to Ukraine.
After winning the Russian election on Sunday, Putin said Monday that his country is "ready for nuclear war".
The explosion could be seen in the distance. (Image: Ukraine Defence/X)
Prime Minister of Estonia, Kaja Kallas told the BBC that Putin is "afraid" of such a conflict despite his bluster.
She said: “Of course, we have to take everything seriously, what he says. He has been threatening nuclear war for quite some time, but it has been only words.
“He’s very good at sowing fear within our societies, really listening to what we are afraid of, and giving you the fears that you have.”
Kallas added that Putin understands people are “afraid of the nuclear war."